Overseas Employment

Would accepting a job outside the US hinder the chances at succeeding on a self-petition? Facts of the case:

– Graduated with PhD in 2014 from University of Washington (Biostatistician with multiple publications, multiple (US and international) conference participation and awards)
– Home country has granted J-1 waiver
– Accepted position in Africa with the US-based CDC (Center for Disease Control)
– Family still in the US while I “commute” every two months between US and Kenya (entry is dependent on current trip focus: visitor or business (conference attendee)

Would it be better to be  a Post-Doc rather than working internationally for the CDC? At this time, there is no plan for the CDC to sponsor the green card process.